Genetic factors contributing to ‘strabismus’ — or misaligned eyes


Researchers have discovered a key gene for generating eye movements. Using zebrafish, they developed a compelling model system to analyze the brain-eye muscle connections, and found that the brain neurons use repulsive forces mediated by a protein encoded by the protocadherin 17 gene to position properly and reach the target eye muscle. The findings potentially contribute to treatment of congenital eye movement disorders.

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